AOD-9604 (5 mg, 10 mg)
C-terminal hGH fragment analogue for fat metabolism research
CAS No.
221231-10-3
Mol. weight
~ 1815 g/mol
Purity
>99% HPLC
Form
White lyophilized powder
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Research use only
AOD-9604 is a synthetic peptide fragment derived from the C-terminal region of human growth hormone (hGH), corresponding to amino acids 177–191. Unlike full-length hGH, AOD-9604 is designed to retain fat-reducing properties without affecting insulin sensitivity or inducing growth-promoting activity. Preclinical studies show that AOD-9604 stimulates lipolysis, inhibits lipogenesis, and may enhance fat oxidation. This makes it a valuable tool for exploring obesity, metabolic disorders, and energy regulation in experimental models.
| Synonyms | AOD-9604, hGH fragment (177–191) analogue |
| Sequence | Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (modified analogue) |
| Molecular Formula | C78H123N23O23S2 |
| Molecular Weight | ~ 1815 g/mol |
| CAS Number | 221231-10-3 |
| Appearance | White lyophilized powder |
Supplied as a lyophilized powder in vials (5 mg). Store at –20 °C, protected from light and moisture. After reconstitution in sterile water or buffer, aliquot and store at 2–8 °C for short-term use or –20 °C for long-term preservation. Avoid repeated freeze–thaw cycles to maintain integrity.
For laboratory research use only. Not for human or veterinary use. Not a drug, food, or cosmetic.
Certificate of Analysis
Third-party tested · HPLC verified on every batch
Sources & References
Peer-reviewed literature underpinning this research compound
- Ng FM, Sun J, Sharma L, Libinaka R, Jiang WJ, Gianello R Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone. Hormone Research, 2000. PubMed ↗
- Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. Endocrinology, 2001. PubMed ↗
- Wilding JP Review of metabolic profile and investigational history of AOD9604. Current Opinion in Investigational Drugs, 2004. PubMed ↗
References are provided for scientific background only. Atomix Research compounds are sold strictly for in-vitro laboratory and research use and are not intended to diagnose, treat, cure, or prevent any disease.
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Important notes
- Intended for research and laboratory use only.
- Must be handled by qualified research professionals.
- Store in a cool, dry place away from direct sunlight.
- Keep out of reach of children and unauthorized individuals.
- Follow all applicable local regulations regarding research compounds.