Research use only

MOTS-C is a 16–amino acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA. It has been studied for its role in regulating metabolism, insulin sensitivity, and cellular stress responses. Preclinical research indicates MOTS-C activates the AMPK pathway, enhances glucose utilization, promotes fatty acid oxidation, and improves exercise tolerance. It has also been linked to protective effects against obesity-related metabolic dysfunction, oxidative stress, and age-associated decline, making it a valuable tool in the field of mitochondrial and metabolic biology research.